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Prescribing Information

Before administering Quadracel vaccine, please see full Prescribing Information.
 

Reimbursement Information

Quadracel®

Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine (DTaP-IPV)
For children 4 through 6 years of age

Coming Soon

About Quadracel Vaccine

IMPORTANT SAFETY INFORMATION FOR QUADRACEL VACCINE

Contraindications to vaccination with Quadracel vaccine include: severe allergic reaction (eg, anaphylaxis) to any ingredient of Quadracel vaccine or following any other diphtheria toxoid, tetanus toxoid, or pertussis-containing vaccine, or inactivated poliovirus vaccine; encephalopathy within 7 days after a previous dose of a pertussis-containing vaccine with no other identifiable cause; or a progressive neurologic disorder.

Carefully consider benefits and risks before administering Quadracel vaccine to persons with a history of: fever ≥105°F, hypotonic-hyporesponsive episode (HHE), or persistent, inconsolable crying lasting 3 hours within 48 hours after a previous pertussis-containing vaccine; seizures within 3 days after a previous pertussis-containing vaccine; Guillain-Barré syndrome occurring within 6 weeks following receipt of a prior vaccine containing tetanus toxoid; or adverse events after a previous dose of Quadracel vaccine or receipt of any other tetanus toxoid, diphtheria toxoid, or pertussis antigen-containing vaccine.

The most common local and systemic adverse reactions to Quadracel vaccine include pain, erythema, and edema at the injection site; myalgia, malaise, and headache. Other adverse reactions may occur. Vaccination with Quadracel vaccine may not protect all individuals.

INDICATION FOR QUADRACEL VACCINE

Quadracel vaccine is indicated for active immunization against diphtheria, tetanus, pertussis, and poliomyelitis.

A single dose of Quadracel vaccine is approved for use in children 4 through 6 years of age as a fifth dose in the diphtheria, tetanus, pertussis vaccination (DTaP) series, and as a fourth or fifth dose in the inactivated poliovirus vaccination (IPV) series, in children who have received 4 doses of Pentacel® (Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate [Tetanus Toxoid Conjugate] Vaccine) and/or DAPTACEL® (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed). .

Before administering Quadracel vaccine, please see accompanying full Prescribing Information.

 

CDC VIS Sheets

 
Vaccine Information Statement

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